BDBM322714 2-(azepan-1-yl)-4-((4-((4-(2-hydroxy-2- methylpropanoyl)piperazin-1-yl)methyl) phenyl)amino)pyrimido[4,5-d]pyridazin- 5(6H)-one::US10183944, Example 84::US10647720, Ex. # 84
SMILES CC(C)(O)C(=O)N1CCN(Cc2ccc(Nc3nc(nc4cn[nH]c(=O)c34)N3CCCCCC3)cc2)CC1
InChI Key InChIKey=DOUZNVZUHNFDDG-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 322714
Affinity DataIC50: <50nMAssay Description:2.5 μL of 10% DMSO or compound in 10% DMSO was added to the wells in a 96 well V-bottom plate. Optimized concentration of in-house Syk enzyme (d...More data for this Ligand-Target Pair
Affinity DataIC50: <10nMAssay Description:Two μL of 10% DMSO in blank, substrate control and positive control wells and 2 μL of test compound in test wells was added. Thirteen μ...More data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:2.5 μL of 10% DMSO or compound in 10% DMSO was added to the wells in a 96 well V-bottom plate. Optimized concentration of in-house Syk enzyme (d...More data for this Ligand-Target Pair
Affinity DataIC50: <10nMAssay Description:Two μL of 10% DMSO in blank, substrate control and positive control wells and 2 μL of test compound in test wells was added. Thirteen μ...More data for this Ligand-Target Pair