BDBM322762 3-(1-(4-((5-oxo-2-phenyl-5,6- dihydropyrimido[4,5-d]pyridazin-4-yl) amino)phenyl)piperidin-4-yl)propanoic acid::US10183944, Example 132::US10647720, Ex. # 132
SMILES OC(=O)CCC1CCN(CC1)c1ccc(Nc2nc(nc3cn[nH]c(=O)c23)-c2ccccc2)cc1
InChI Key InChIKey=FPSCWKHRIRPRNQ-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 322762
Affinity DataIC50: 10nMAssay Description:Two μL of 10% DMSO in blank, substrate control and positive control wells and 2 μL of test compound in test wells was added. Thirteen μ...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Two μL of 10% DMSO in blank, substrate control and positive control wells and 2 μL of test compound in test wells was added. Thirteen μ...More data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:2.5 μL of 10% DMSO or compound in 10% DMSO was added to the wells in a 96 well V-bottom plate. Optimized concentration of in-house Syk enzyme (d...More data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:2.5 μL of 10% DMSO or compound in 10% DMSO was added to the wells in a 96 well V-bottom plate. Optimized concentration of in-house Syk enzyme (d...More data for this Ligand-Target Pair