BDBM32363 (4-chlorophenyl)-[4-(4-pyridylmethyl)phthalazin-1-yl]amine

SMILES Clc4ccc(Nc2nnc(Cc1ccncc1)c3ccccc23)cc4

InChI Key InChIKey=YCOYDOIWSSHVCK-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 32363   

TargetMast/stem cell growth factor receptor Kit(Human)
Knight Cancer Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 32363BDBM32363((4-chlorophenyl)-[4-(4-pyridylmethyl)phthalazin-1-...)
Affinity DataIC50: 7.94E+3nMAssay Description:Inhibition of KIT in Melphalan Resistant human RPMI-8226 cells assessed as reduction of cell growth incubated for 72 hrs by CellTiter 96 aqueous one ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Knight Cancer Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 32363BDBM32363((4-chlorophenyl)-[4-(4-pyridylmethyl)phthalazin-1-...)
Affinity DataIC50: 9.77E+3nMAssay Description:Inhibition of KIT in human RPMI-8226 cells assessed as reduction of cell growth incubated for 72 hrs by CellTiter 96 aqueous one solution cell prolif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Knight Cancer Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 32363BDBM32363((4-chlorophenyl)-[4-(4-pyridylmethyl)phthalazin-1-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of KIT in human U-266 cells assessed as reduction of cell growth incubated for 72 hrs by CellTiter 96 aqueous one solution cell proliferat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Knight Cancer Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 32363BDBM32363((4-chlorophenyl)-[4-(4-pyridylmethyl)phthalazin-1-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of KIT in human ANBL-6 cells assessed as reduction of cell growth incubated for 72 hrs by CellTiter 96 aqueous one solution cell prolifera...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Knight Cancer Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 32363BDBM32363((4-chlorophenyl)-[4-(4-pyridylmethyl)phthalazin-1-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of KIT in bortezomib Resistant human RPMI-8226 cells assessed as reduction of cell growth incubated for 72 hrs by CellTiter 96 aqueous one...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Knight Cancer Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 32363BDBM32363((4-chlorophenyl)-[4-(4-pyridylmethyl)phthalazin-1-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of KIT in human bortezomib-resistant ANBL6 cells assessed as reduction of cell growth incubated for 72 hrs by CellTiter 96 aqueous one sol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed