BDBM324915 7-(1,1-dioxidothietan-3-::US10189841, Compound I-121::US10399980, Compound I-121::US11161848, Compound I-121

SMILES CC(C)c1ncccc1-c1ncc2n(C3CS(=O)(=O)C3)c(=O)n(Cc3ccc(cc3)-c3nc(cn3C)C(F)(F)F)c2n1

InChI Key InChIKey=LOPAZQRSEQHQIO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 324915   

TargetUbiquitin carboxyl-terminal hydrolase 1(Human)
Forma Therapeutics

US Patent
LigandPNGBDBM324915(7-(1,1-dioxidothietan-3- | US10189841, Compound I-...)
Affinity DataIC50: 200nMAssay Description:The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase 1(Human)
Forma Therapeutics

US Patent
LigandPNGBDBM324915(7-(1,1-dioxidothietan-3- | US10189841, Compound I-...)
Affinity DataIC50: 1.10E+3nMAssay Description:The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2022
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase 1(Human)
Forma Therapeutics

US Patent
LigandPNGBDBM324915(7-(1,1-dioxidothietan-3- | US10189841, Compound I-...)
Affinity DataIC50: 1.10E+3nMAssay Description:The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details
US Patent