BDBM32544 arylsulfonylpiperazine, 16

SMILES FC(F)(F)c1cccnc1N1CCN(CC1)S(=O)(=O)c1ccc(cc1)C#N

InChI Key InChIKey=OULXRFUMARETNV-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 32544   

LigandPNGBDBM32544(arylsulfonylpiperazine, 16)
Affinity DataIC50: 50nM EC50:  978nMpH: 7.2 T: 2°CAssay Description:Enzyme assays were performed using purified recombinant human 11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2009
Entry Details Article
PubMed
LigandPNGBDBM32544(arylsulfonylpiperazine, 16)
Affinity DataIC50: 546nMAssay Description:Enzyme assays were performed using purified recombinant human 11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2009
Entry Details Article
PubMed