BDBM32587 1-aza-2-oxobicyclo[5.3.0]decane scaffold, 16a

SMILES CC[C@H](N)C(=O)N[C@@H]1C(=O)N2[C@@H](CC[C@@H]1CN=C(N)N)CC[C@H]2C(=O)NC(c1ccccc1)c1ccccc1

InChI Key InChIKey=JXUHBFWPZHCAKE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 32587   

TargetE3 ubiquitin-protein ligase XIAP(Human)
Universita Degli Studi Di Milano

LigandChemical structure of BindingDB Monomer ID 32587BDBM32587(1-aza-2-oxobicyclo[5.3.0]decane scaffold, 16a)
Affinity DataIC50: 390nMAssay Description:Fluorescence polarization was measured on an Ultra plate reader (Tecan) at excitation and emission wavelengths of 485 and 530 nm, respectively. The e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2009
Entry Details Article
PubMed
TargetBaculoviral IAP repeat-containing protein 3(Human)
Universita Degli Studi Di Milano

LigandChemical structure of BindingDB Monomer ID 32587BDBM32587(1-aza-2-oxobicyclo[5.3.0]decane scaffold, 16a)
Affinity DataIC50: 4.40E+3nMpH: 7.5 T: 2°CAssay Description:Fluorescence polarization was measured on an Ultra plate reader (Tecan) at excitation and emission wavelengths of 485 and 530 nm, respectively. The e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2009
Entry Details Article
PubMed