BDBM326424 US9662327, Compound 121

SMILES Cc1cc(C(=O)N2CCN(CC2)c2nc(C3CCCCC3)c3COCCc3c2C#N)c(C)o1

InChI Key InChIKey=IQTOHJWSHYCIOB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 326424   

TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Human)
Agios Pharmaceuticals

US Patent
LigandPNGBDBM326424(US9662327, Compound 121)
Affinity DataIC50: 5.50E+3nMAssay Description:Assays were conducted in a volume of 76 μl assay buffer (150 mM NaCl, 10 mM MgCl2, 20 mM Tris pH 7.5, 0.03% bovine serum albumin) as follows in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2019
Entry Details
US Patent