BDBM326445 US9662327, Compound 142

SMILES CC1(C)Cc2c(CO1)c(nc(N1CCN(CC1)C(=O)c1ccco1)c2C#N)C1CC1

InChI Key InChIKey=OOIHYQJVEVBYCV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 326445   

TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Human)
Agios Pharmaceuticals

US Patent
LigandPNGBDBM326445(US9662327, Compound 142)
Affinity DataIC50: 5.50E+3nMAssay Description:Assays were conducted in a volume of 76 μl assay buffer (150 mM NaCl, 10 mM MgCl2, 20 mM Tris pH 7.5, 0.03% bovine serum albumin) as follows in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2019
Entry Details
US Patent