BDBM327186 1-[(S)-4-(2,3-Dihydro- [1,4]dioxino[2,3-b]pyridin-3-yl)- benzyl]-4-phenyl-piperidin-4-ol::US9662339, 269

SMILES OC1(CCN(Cc2ccc(cc2)[C@H]2COc3cccnc3O2)CC1)c1ccccc1

InChI Key InChIKey=UVMJYVNJUCRSAK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 327186   

TargetLeukotriene A-4 hydrolase(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM327186(1-[(S)-4-(2,3-Dihydro- [1,4]dioxino[2,3-b]pyridin...)
Affinity DataIC50: 0.200nMAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2019
Entry Details
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