BDBM327192 (S)-3-[4-(1,1-Dioxo-1lambda6- [1,4]thiazepan-4-ylmethyl)- phenyl]-2,3-dihydro- [1,4]dioxino[2,3-b]pyridine::US9662339, 275

SMILES O=S1(=O)CCCN(Cc2ccc(cc2)[C@H]2COc3cccnc3O2)CC1

InChI Key InChIKey=AYBQTOQZCSLBPB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 327192   

TargetLeukotriene A-4 hydrolase(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM327192((S)-3-[4-(1,1-Dioxo-1lambda6- [1,4]thiazepan-4-yl...)
Affinity DataIC50: 0.700nMAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2019
Entry Details
US Patent