BDBM328085 N-(1-(4-methoxybenzyl) piperidin-4-yl)-6-(4-(4- (methylsulfonyl) benzoyl)piperidine-1- carbonyl)nicotinamide::US9663496, Compound 223

SMILES COc1ccc(CN2CCC(CC2)NC(=O)c2ccc(nc2)C(=O)N2CCC(CC2)C(=O)c2ccc(cc2)S(C)(=O)=O)cc1

InChI Key InChIKey=LQCGDAYXUKPYRS-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 328085   

Target5'-AMP-activated protein kinase catalytic subunit alpha-2(Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM328085(US9663496, Compound 223 | N-(1-(4-methoxybenzyl) ...)
Affinity DataEC50:  3.00E+3nMAssay Description:Compounds were assayed for their ability to activate AMPK using an enzyme-linked immunosorbent assay. Reagents and procedures for measuring AMPK acti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
US Patent