BDBM328098 N-(1-(3,5- difluorobenzyl)piperidin- 4-yl)-6-(4-(4- (methylsulfonyl) phenoxy)piperidine-1- carbonyl)nicotinamide::US9663496, Compound 236

SMILES CS(=O)(=O)c1ccc(OC2CCN(CC2)C(=O)c2ccc(cn2)C(=O)NC2CCN(Cc3cc(F)cc(F)c3)CC2)cc1

InChI Key InChIKey=SCLZKSLYQIVDQL-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 328098   

Target5'-AMP-activated protein kinase catalytic subunit alpha-2(Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM328098(US9663496, Compound 236 | N-(1-(3,5- difluorobenzy...)
Affinity DataEC50: <500nMAssay Description:Compounds were assayed for their ability to activate AMPK using an enzyme-linked immunosorbent assay. Reagents and procedures for measuring AMPK acti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
US Patent