BDBM328177 N-((1s,4s)-4-(4- cyanophenoxy) cyclohexyl)-6-(4-(4- methoxybenzoyl) piperidine-1- carbonyl)nicotinamide::US9663496, Compound 315

SMILES COc1ccc(cc1)C(=O)C1CCN(CC1)C(=O)c1ccc(cn1)C(=O)NC1CC[C@@H](CC1)Oc1ccc(cc1)C#N

InChI Key InChIKey=BUASOVJVWXZVAK-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 328177   

Target5'-AMP-activated protein kinase catalytic subunit alpha-2(Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM328177(US9663496, Compound 315 | N-((1s,4s)-4-(4- cyanoph...)
Affinity DataEC50: <500nMAssay Description:Compounds were assayed for their ability to activate AMPK using an enzyme-linked immunosorbent assay. Reagents and procedures for measuring AMPK acti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
US Patent