BDBM328197 6-(4-(4-cyanophenoxy) piperidine-1-carbonyl)- N-(piperidin-4- yl)nicotinamide::US10377742, Compound 335::US9663496, Compound 335

SMILES O=C(NC1CCNCC1)c1ccc(nc1)C(=O)N1CCC(CC1)Oc1ccc(cc1)C#N

InChI Key InChIKey=QLERZABOMGLECS-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 328197   

Target5'-AMP-activated protein kinase catalytic subunit alpha-2(Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM328197(US9663496, Compound 335 | 6-(4-(4-cyanophenoxy) p...)
Affinity DataEC50: >1.00E+4nMAssay Description:Compounds were assayed for their ability to activate AMPK using an enzyme-linked immunosorbent assay. Reagents and procedures for measuring AMPK acti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
Go to US Patent

Target5'-AMP-activated protein kinase catalytic subunit alpha-2(Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM328197(US9663496, Compound 335 | 6-(4-(4-cyanophenoxy) p...)
Affinity DataEC50: >1.00E+4nMAssay Description:Compounds were assayed for their ability to activate AMPK using an enzyme-linked immunosorbent assay. Reagents and procedures for measuring AMPK acti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
Go to US Patent