BDBM328296 N-((cis)-4-(4- cyanophenoxy) cyclohexyl)-6-(4-(3- (cyclopropane- carboxamido)phenoxy) piperidine-1- carbonyl)nicotinamide::US9663496, Compound 434

SMILES O=C(Nc1cccc(OC2CCN(CC2)C(=O)c2ccc(cn2)C(=O)NC2CC[C@@H](CC2)Oc2ccc(cc2)C#N)c1)C1CC1

InChI Key InChIKey=JKWVHOJBLXODFV-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 328296   

Target5'-AMP-activated protein kinase catalytic subunit alpha-2(Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM328296(US9663496, Compound 434 | N-((cis)-4-(4- cyanophen...)
Affinity DataEC50: <500nMAssay Description:Compounds were assayed for their ability to activate AMPK using an enzyme-linked immunosorbent assay. Reagents and procedures for measuring AMPK acti...More data for this Ligand-Target Pair
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Date in BDB:
6/4/2019
Entry Details
Go to US Patent