BDBM328656 (S)-3,3,3-trifluoropropyl (2- (acetamidomethyl)-4-((4- fluorophenyl)sulfonyl)-3,4- dihydro-2H-benzo[b][1,4]oxazin-6- yl)carbamate::US9663502, 30P

SMILES CC(=O)NC[C@H]1CN(c2cc(NC(=O)OCCC(F)(F)F)ccc2O1)S(=O)(=O)c1ccc(F)cc1

InChI Key InChIKey=RLNCULMLYCDCIX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 328656   

TargetNuclear receptor ROR-gamma(Human)
Lycera

US Patent
LigandPNGBDBM328656((S)-3,3,3-trifluoropropyl (2- (acetamidomethyl)-4-...)
Affinity DataIC50: 216nMAssay Description:The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., a biochemical TR-FRET assay....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
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