BDBM328658 (S)-2,2,2-trichloroethyl (2- (acetamidomethyl)-4-((4- fluorophenyl)sulfonyl)-3,4- dihydro-2H-benzo[b][1,4]oxazin-6- yl)carbamate::US9663502, 30R

SMILES CC(=O)NC[C@H]1CN(c2cc(NC(=O)OCC(Cl)(Cl)Cl)ccc2O1)S(=O)(=O)c1ccc(F)cc1

InChI Key InChIKey=OAEJZZFKQHLRQD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 328658   

TargetNuclear receptor ROR-gamma(Human)
Lycera

US Patent
LigandPNGBDBM328658((S)-2,2,2-trichloroethyl (2- (acetamidomethyl)-4-(...)
Affinity DataIC50: 11nMAssay Description:The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., a biochemical TR-FRET assay....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
US Patent