BDBM328660 (S)-2,2,2-trichloroethyl (2- (cyclopropanecarboxamidomethyl)- 4-((4-fluorophenyl)sulfonyl)-3,4- dihydro-2H-benzo[b][1,4]oxazin-6- yl)carbamate::US9663502, 30T

SMILES Fc1ccc(cc1)S(=O)(=O)N1C[C@H](CNC(=O)C2CC2)Oc2ccc(NC(=O)OCC(Cl)(Cl)Cl)cc12

InChI Key InChIKey=HPATWWMACUQYLQ-INIZCTEOSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 328660   

TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Lycera

US Patent
LigandPNGBDBM328660((S)-2,2,2-trichloroethyl (2- (cyclopropanecarboxam...)
Affinity DataIC50:  8.09nMAssay Description:The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., a biochemical TR-FRET assay....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent