BDBM328670 1-cyclopropylethyl ((S)-2- (acetamidomethyl)-4-((4- fluorophenyl)sulfonyl)-3,4- dihydro-2H-benzo[b][1,4]oxazin-6- yl)carbamate::US9663502, 30AD

SMILES CC(OC(=O)Nc1ccc2O[C@@H](CNC(C)=O)CN(c2c1)S(=O)(=O)c1ccc(F)cc1)C1CC1

InChI Key InChIKey=LAAXGNRBKYPGNB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 328670   

TargetNuclear receptor ROR-gamma(Human)
Lycera

US Patent
LigandPNGBDBM328670(1-cyclopropylethyl ((S)-2- (acetamidomethyl)-4-((4...)
Affinity DataIC50: 404nMAssay Description:The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., a biochemical TR-FRET assay....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
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