BDBM328681 (S)-neopentyl (2- (cyclopropanecarboxamidomethyl)-4-((4- fluorophenyl)sulfonyl)-3,4-dihydro-2H- benzo[b][1,4]oxazin-6-yl)carbamate::US9663502, 32i

SMILES CC(C)(C)COC(=O)Nc1ccc2O[C@@H](CNC(=O)C3CC3)CN(c2c1)S(=O)(=O)c1ccc(F)cc1

InChI Key InChIKey=GFZCCVOMCNEXIL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 328681   

TargetNuclear receptor ROR-gamma(Human)
Lycera

US Patent
LigandPNGBDBM328681((S)-neopentyl (2- (cyclopropanecarboxamidomethyl)-...)
Affinity DataIC50: 16.8nMAssay Description:The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., a biochemical TR-FRET assay....More data for this Ligand-Target Pair
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Date in BDB:
6/4/2019
Entry Details
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