BDBM32872 MLS000391277::N-[(Z)-(3-amino-1-isoindolylidene)amino]-4-(4-chlorophenyl)-2-thiazolamine::N-[(Z)-(3-aminoisoindol-1-ylidene)amino]-4-(4-chlorophenyl)-1,3-thiazol-2-amine::N-[(Z)-(3-azanylisoindol-1-ylidene)amino]-4-(4-chlorophenyl)-1,3-thiazol-2-amine::SMR000260314::[(Z)-(3-aminoisoindol-1-ylidene)amino]-[4-(4-chlorophenyl)thiazol-2-yl]amine::cid_6160946

SMILES NC1=NC(=NNc2nc(-c3ccc(Cl)cc3)cs2)c2ccccc21

InChI Key InChIKey=OLVORKOOPWSYGY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 32872   

TargetCoagulation factor XII(Human)
Pcmd

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 32872BDBM32872(SMR000260314 | cid_6160946 | MLS000391277 | N-[(Z)...)
Affinity DataIC50: 5.00E+4nMAssay Description:Molecular Library Screening Center Network (MLSCN) Penn Center for Molecular Discovery (PCMD) Assay Provider: Scott L. Diamond, University of Pennsy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2011
Entry Details
PCBioAssay
TargetCoagulation factor XI(Human)
Pcmd

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 32872BDBM32872(SMR000260314 | cid_6160946 | MLS000391277 | N-[(Z)...)
Affinity DataIC50: 5.00E+4nMpH: 7.4 T: 2°CAssay Description:Factor XIa (0.23 ug/mL) was incubated with Boc-Glu-Ala-Arg-AMC substrate (15 uM) in 10 uL of assay buffer for 2 hr at room temperature. Read fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2009
Entry Details
PCBioAssay