BDBM328816 (S)-tert-butyl (4-((3- cyanophenyl)sulfonyl)-2- (cyclopropanesulfonamidomethyl)-3,4- dihydro-2H-benzo[b][1,4]oxazin-6- yl)carbamate::US9663502, 36L

SMILES CC(C)(C)OC(=O)Nc1ccc2O[C@@H](CNS(=O)(=O)C3CC3)CN(c2c1)S(=O)(=O)c1cccc(c1)C#N

InChI Key InChIKey=MLQPSWPKLJIHNS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 328816   

TargetNuclear receptor ROR-gamma(Human)
Lycera

US Patent
LigandPNGBDBM328816(US9663502, 36L | (S)-tert-butyl (4-((3- cyanopheny...)
Affinity DataIC50: 4.60nMAssay Description:The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., a biochemical TR-FRET assay....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
US Patent