BDBM331365 5-(Dimethyl-1H-1,2,3-triazol-5-yl)-N-methyl-8-[(S)-oxan-4-yl(phenyl)methyl]-3,8,10-triazatricyclo[7.4.0.02,7]trideca-1(9),2::US9725449, Example 199

SMILES CNS(=O)(=O)c1ccc2c(n1)n([C@@H](C1CCOCC1)c1ccccc1)c1cc(cnc21)-c1c(C)nnn1C

InChI Key InChIKey=CNNGAOACROEUGE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 331365   

LigandPNGBDBM331365(5-(Dimethyl-1H-1,2,3-triazol-5-yl)-N-methyl-8-[(S)...)
Affinity DataIC50: 10nMAssay Description:The binding of compounds to bromodomain BRD4 (44-168), BRD4 (333-460), and BRD4 (1-477 or 44-460) was assessed using a time resolved fluorescent reso...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
US Patent