BDBM331679 US9725465, Example 100

SMILES CN(C)CCNC(=O)c1n[nH]c2ncc(cc12)-c1ccc(CC(=O)Nc2cc(on2)C(C)(C)C)cc1

InChI Key InChIKey=RAZYIXVNZNLJSZ-UHFFFAOYSA-N

Data  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 331679   

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Ambit Biosciences

US Patent
LigandPNGBDBM331679(US9725465, Example 100)
Affinity DataKd: <5nMAssay Description:Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
Go to US Patent

TargetMast/stem cell growth factor receptor Kit(Human)
Ambit Biosciences

US Patent
LigandPNGBDBM331679(US9725465, Example 100)
Affinity DataKd:  12.5nMAssay Description:Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
Go to US Patent