BDBM331956 US10189859, Compound 199::methyl 2-((2-(2-((5-amino-6-(2,3-dichlorophenyl)-1,2,4-triazin-3-yl)amino)ethoxy)ethyl)amino)acetate

SMILES COC(=O)CNCCOCCNc1nnc(c(N)n1)-c1cccc(Cl)c1Cl

InChI Key InChIKey=IWEPHTSBKMWDGJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 331956   

TargetSodium channel protein type 9 subunit alpha(Human)
Nektar Therapeutics

US Patent
LigandPNGBDBM331956(US10189859, Compound 199 | methyl 2-((2-(2-((5-ami...)
Affinity DataIC50: 2.00E+5nMAssay Description:The potencies of the compounds provided herein to block specific Na+ channels was measured using automated patch clamp electrophysiologically of Nav1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
US Patent

TargetSodium channel protein type 9 subunit alpha(Human)
Nektar Therapeutics

US Patent
LigandPNGBDBM331956(US10189859, Compound 199 | methyl 2-((2-(2-((5-ami...)
Affinity DataIC50: 3.00E+5nMAssay Description:The potencies of the compounds provided herein to block specific Na+ channels was measured using automated patch clamp electrophysiologically of Nav1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
US Patent