BDBM331960 US10189859, Compound 203::tert-butyl 2-(2-(4-(5-amino-6-(2,3-dichlorophenyl)-1,2,4-triazin-3-yl)piperazin-1-yl)ethoxy)acetate

SMILES CC(C)(C)OC(=O)COCCN1CCN(CC1)c1nnc(c(N)n1)-c1cccc(Cl)c1Cl

InChI Key InChIKey=ZETYNAJTTJPYII-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 331960   

TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Nektar Therapeutics

US Patent
LigandPNGBDBM331960(US10189859, Compound 203 | tert-butyl 2-(2-(4-(5-a...)
Affinity DataIC50: <5.00E+4nMAssay Description:The potencies of the compounds provided herein to block specific Na+ channels was measured using automated patch clamp electrophysiologically of Nav1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Nektar Therapeutics

US Patent
LigandPNGBDBM331960(US10189859, Compound 203 | tert-butyl 2-(2-(4-(5-a...)
Affinity DataIC50:  8.79E+4nMAssay Description:The potencies of the compounds provided herein to block specific Na+ channels was measured using automated patch clamp electrophysiologically of Nav1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent