BDBM333371 Methyl2-chloro-5-(((3-((2S,3R,4S)-3,4-dihydroxytetrahydrothiophen-2-yl)imidazo[1,2-a]pyrazin-8-yl)amino)methyl)benzoate::US10196396, Compound 182

SMILES COC(=O)c1cc(CNc2nccn3c(cnc23)[C@@H]2SC[C@@H](O)[C@H]2O)ccc1Cl

InChI Key InChIKey=AIJJJJWEPIRYCR-OAGGEKHMSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 333371   

TargetAdenosine receptor A3(Homo sapiens (Human))
Handok

US Patent
LigandPNGBDBM333371(Methyl2-chloro-5-(((3-((2S,3R,4S)-3,4-dihydroxytet...)
Affinity DataIC50:  55nMAssay Description:HEK-293 cell membrane homogenates (32 μg protein), in which A3 adenosine receptors were expressed, are incubated for 120 min at 22° C. with 0.15...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent