BDBM334221 US9730940, Compound 9-1::US9730940, Compound 9-2::cis-tert-butyl [(1S,3R)-3-{[8-(1- ethyl-5-methyl-1H-pyrazol-4- yl)-9-methyl-9H-purin-6- yl]oxy}cyclopentyl]carbamate

SMILES CCn1ncc(c1C)-c1nc2c(OC3CCC(C3)NC(=O)OC(C)(C)C)ncnc2n1C

InChI Key InChIKey=PRFSFXUBDCSISV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 334221   

LigandPNGBDBM334221(US9730940, Compound 9-2 | cis-tert-butyl [(1S,3R)-...)
Affinity DataIC50: 140nMAssay Description:The PI3-Kinase biochemical assay was optimized using the HTRF kit provided by Upstate (Millipore). The assay kit contains six reagents: 1) 4× Reactio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2019
Entry Details
US Patent

LigandPNGBDBM334221(US9730940, Compound 9-2 | cis-tert-butyl [(1S,3R)-...)
Affinity DataIC50: 400nMAssay Description:The PI3-Kinase biochemical assay was optimized using the HTRF kit provided by Upstate (Millipore). The assay kit contains six reagents: 1) 4× Reactio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2019
Entry Details
US Patent