BDBM334225 US9730940, Compound 9-5::tert-butyl (cis-3-{[9-ethyl-8-(2- methylpyrimidin-5-yl)-9H- purin-6- yl]oxy}cyclobutyl)carbamate

SMILES CCn1c(nc2c(O[C@@H]3C[C@@H](C3)NC(=O)OC(C)(C)C)ncnc12)-c1cnc(C)nc1

InChI Key InChIKey=GZVHLVAXJVAIDB-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 334225   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Merck Sharp & Dohme

US Patent

LigandBDBM334225(tert-butyl (cis-3-{[9-ethyl-8-(2- methylpyrimidin-...)Copy SMILESCopy InChI

Affinity DataIC50: 96nMAssay Description:The PI3-Kinase biochemical assay was optimized using the HTRF kit provided by Upstate (Millipore). The assay kit contains six reagents: 1) 4× Reactio...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
6/23/2019
Entry Details
Copy Entry DOIGo to US Patent

Copy Rxn URL