BDBM334227 N-(trans-4-{[9-ethyl-8-(2- methylpyrimidin-5-yl)-9H- purin-6- yl]oxy}cyclohexyl)propanamide::US9730940, Compound 9-7

SMILES CCC(=O)N[C@H]1CC[C@@H](CC1)Oc1ncnc2n(CC)c(nc12)-c1cnc(C)nc1

InChI Key InChIKey=OJWPCUYSBMLDOJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 334227   

LigandPNGBDBM334227(N-(trans-4-{[9-ethyl-8-(2- methylpyrimidin-5-yl)-9...)
Affinity DataIC50: 330nMAssay Description:The PI3-Kinase biochemical assay was optimized using the HTRF kit provided by Upstate (Millipore). The assay kit contains six reagents: 1) 4× Reactio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2019
Entry Details
US Patent