BDBM334229 N-[(1S,3S) or (1R,3R)]-(3-{[9- ethyl-8-(2-methylpyrimidin-5- yl)-9H-purin-6- yl]oxy}cyclopentyl)tetrahydro- 2H-pyran-4-carboxamide::US9730940, Compound 9-9

SMILES CCn1c(nc2c(OC3CCC(C3)NC(=O)C3CCOCC3)ncnc12)-c1cnc(C)nc1

InChI Key InChIKey=GLAZPZCMSPKPSU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 334229   

LigandPNGBDBM334229(N-[(1S,3S) or (1R,3R)]-(3-{[9- ethyl-8-(2-methylpy...)
Affinity DataIC50: 170nMAssay Description:The PI3-Kinase biochemical assay was optimized using the HTRF kit provided by Upstate (Millipore). The assay kit contains six reagents: 1) 4× Reactio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2019
Entry Details
US Patent