BDBM334230 US9730940, Compound 9-10::trans-N-(3-{[9-ethyl-8-(2- methylpyrimidin-5-yl)-9H- purin-6- yl]oxy}cyclobutyl) ethanesulfonamide

SMILES CCn1c(nc2c(OC3C[C@@H](C3)NS(=O)(=O)CC)ncnc12)-c1cnc(C)nc1

InChI Key InChIKey=BTIHTOMTGBLSBP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 334230   

LigandPNGBDBM334230(trans-N-(3-{[9-ethyl-8-(2- methylpyrimidin-5-yl)-9...)
Affinity DataIC50: 150nMAssay Description:The PI3-Kinase biochemical assay was optimized using the HTRF kit provided by Upstate (Millipore). The assay kit contains six reagents: 1) 4× Reactio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2019
Entry Details
US Patent