BDBM335716 N-((6,8-Difluoro-1-methyl-3-oxo- 2,3-dihydroisoquinolin-4- yl)methyl)-5-(ethyl(tetrahydro- 2H-pyran-4-yl)amino)-4-methyl- 4'-(morpholinomethyl)-[1,1'- biphenyl]-3-carboxamide::US9738630, Example 11

SMILES CCN(c1cc(-c2ccc(CN3CCOCC3)cc2)cc(C(=O)NCc2c(=O)[nH]c(C)c3c(F)cc(F)cc23)c1C)C1CCOCC1

InChI Key InChIKey=SDMGNZSKNHIHSX-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 335716   

TargetHistone-lysine N-methyltransferase EZH2(Human)
Bristol Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 335716BDBM335716(US9738630, Example 11 | N-((6,8-Difluoro-1-methyl-...)
Affinity DataEC50: <5.00E+3nMAssay Description:The effectiveness of compounds of the present invention as inhibitors of hitone methyl transferases can be readily tested by assays known to those sk...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2019
Entry Details
US Patent