BDBM337574 US9745324, 43

SMILES COc1cnc2c(Nc3ccc(F)c(c3)[C@]3(C)CN(C)S(=O)(=O)C(C)(C)C(=N)N3)nccc2c1

InChI Key InChIKey=RKYGTOUJCHJNJL-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 337574   

TargetBeta-secretase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM337574(US9745324, 43)
Affinity DataKi:  209nMAssay Description:Reagents: Na+-Acetate pH 5.0; 1% Brij-35; Glycerol; Dimethyl Sulfoxide (DMSO); Recombinant human soluble BACE1 catalytic domain (>95% pure); APP Swed...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details
US Patent