BDBM337585 5-[3-Fluoro-2'-(1H-pyrazol-4- yl)biphenyl-4-yl]pyrazin-2-amine::US9745328, Compound 870

SMILES Nc1cnc(cn1)-c1ccc(cc1F)-c1ccccc1-c1cn[nH]c1

InChI Key InChIKey=QIWCDXWAZZLMRG-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 337585   

TargetFlap endonuclease 1(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM337585(5-[3-Fluoro-2'-(1H-pyrazol-4- yl)biphenyl-4-yl]pyr...)
Affinity DataKi:  14.3nMAssay Description:The FLAP binding assay is performed in HTRF format (homogeneous time resolved fluorescence). FLAP-containing membranes (1 μg/well final for huma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details
US Patent