BDBM338099 US9751854, Compound I-275::US9802960, Compound I-277

SMILES CN(C(=O)c1cc(cnc1C)-c1ccnc(Nc2ccnc(C)n2)c1)C12CC(C1)C2

InChI Key InChIKey=ASXWGRRNAJQNKY-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 338099   

TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
Millennium Pharmaceuticals

US Patent
LigandPNGBDBM338099(US9751854, Compound I-275 | US9802960, Compound I-...)
Affinity DataIC50: 10nMAssay Description:100 nL compounds in DMSO are added to wells of a 384 well microtitre plate (Greiner 780076). At room temperature: 5 ul VPS34 reaction buffer (Invitro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2019
Entry Details
Go to US Patent

TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
Millennium Pharmaceuticals

US Patent
LigandPNGBDBM338099(US9751854, Compound I-275 | US9802960, Compound I-...)
Affinity DataIC50: 30nMAssay Description:100 nL compounds in DMSO are added to wells of a 384 well microtitre plate (Greiner 780076). At room temperature: 5 ul VPS34 reaction buffer (Invitro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2019
Entry Details
Go to US Patent

TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
Millennium Pharmaceuticals

US Patent
LigandPNGBDBM338099(US9751854, Compound I-275 | US9802960, Compound I-...)
Affinity DataIC50: 30nMAssay Description:100 nL compounds in DMSO are added to wells of a 384 well microtitre plate (Greiner 780076). At room temperature: 5 ul VPS34 reaction buffer (Invitro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2019
Entry Details
Go to US Patent