BDBM338418 US9751873, Example 106::methyl 2-[2,5-difluoro-4-[[(3S,6R)- 3-methyl-1,1-dioxo-6-phenyl- thiazinan-2-yl]methyl]phenyl] acetate

SMILES COC(=O)Cc1cc(F)c(CN2[C@@H](C)CC[C@H](c3ccccc3)S2(=O)=O)cc1F

InChI Key InChIKey=BMQRSYPGLBNAMM-VBKZILBWSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 338418   

TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM338418(US9751873, Example 106 | methyl 2-[2,5-difluoro-4-...)
Affinity DataIC50:  58nMAssay Description:Assays were carried out in 16-microL reaction volumes in black 384 Plus F Proxiplates (Perkin-Elmer 6008269). All assay components except test ligand...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent