BDBM33961 dihydroxy benzoyl naphthyl hydrazone (DHBNH) analogue, 8

SMILES COc1ccc2ccccc2c1\C=N\NC(=O)C1CCC(CC1)c1ccc(Cl)cc1

InChI Key InChIKey=NYSSHZUZNGBACC-JVWAILMASA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 33961   

TargetGag-Pol polyprotein [600-1028,C879S]/[600-1151,C879S](Human immunodeficiency virus type 1)
Rutgers University

LigandPNGBDBM33961(dihydroxy benzoyl naphthyl hydrazone (DHBNH) analo...)
Affinity DataIC50:  1.00E+3nMpH: 7.8 T: 2°CAssay Description:HIV-1 RT RDDP activity was generally determined by a fixed time assay. Briefly, reaction mixtures contained p51/p66 RT, template-primer, and [3H]-TTP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [600-1028,C879S]/[600-1151,C879S](Human immunodeficiency virus type 1)
Rutgers University

LigandPNGBDBM33961(dihydroxy benzoyl naphthyl hydrazone (DHBNH) analo...)
Affinity DataIC50:  7.50E+3nMpH: 8.0 T: 2°CAssay Description:To assess the effect of inhibitors, RT RNH activity was measured using a FRET-based microplate fluorescence assay. Briefly, the RNA-DNA hybrid duplex...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed