BDBM340487 3-[(5-acetyl-1-methyl-6,7-dihydro-4H-pyrazolo[4,3-c]pyridin-3-yl)amino]-N-isopropyl-5-methyl-benzamide::US9763922, Example 18

SMILES CC(C)NC(=O)c1cc(C)cc(Nc2nn(C)c3CCN(Cc23)C(C)=O)c1

InChI Key InChIKey=SEBNBVIRQIWDDS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 340487   

TargetCREB-binding protein(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 340487BDBM340487(US9763922, Example 18 | 3-[(5-acetyl-1-methyl-6,7-...)
Affinity DataIC50: 50nMAssay Description:His/Flag epitope tagged CBP was cloned, expressed, and purified to homogeneity. CBP binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/30/2019
Entry Details
US Patent

TargetBromodomain-containing protein 4(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 340487BDBM340487(US9763922, Example 18 | 3-[(5-acetyl-1-methyl-6,7-...)
Affinity DataIC50: 9.41E+3nMAssay Description:His/Flag epitope tagged BRD4 BD142-168 was cloned, expressed, and purified to. BRD4 binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/30/2019
Entry Details
US Patent