BDBM340512 1-[1-(cyclopropylmethyl)-3-[(2-methylindazol-6-yl)amino]-6,7-dihydro-4H-pyrazolo[4,3-c]pyridin-5-yl]ethanone::US9763922, Example 43

SMILES CC(=O)N1CCc2c(C1)c(Nc1ccc3cn(C)nc3c1)nn2CC1CC1

InChI Key InChIKey=GFYUKKXYYZECKU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 340512   

TargetCREB-binding protein(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 340512BDBM340512(US9763922, Example 43 | 1-[1-(cyclopropylmethyl)-3...)
Affinity DataIC50: 40nMAssay Description:His/Flag epitope tagged CBP was cloned, expressed, and purified to homogeneity. CBP binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/30/2019
Entry Details
US Patent