BDBM340557 1-(1-allyl-3-((3-(1-methyl-1H-pyrazol-4-yl)phenyl)amino)-6,7-dihydro-1H-pyrazolo[4,3-c]pyridin-5(4H)-yl)ethanone::US9763922, Example 87

SMILES CC(=O)N1CCc2c(C1)c(Nc1cccc(c1)-c1cnn(C)c1)cn2CC=C

InChI Key InChIKey=JMLZCGXZLKJYNO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 340557   

TargetCREB-binding protein(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 340557BDBM340557(US9763922, Example 87 | 1-(1-allyl-3-((3-(1-methyl...)
Affinity DataIC50: 20nMAssay Description:His/Flag epitope tagged CBP was cloned, expressed, and purified to homogeneity. CBP binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/30/2019
Entry Details
US Patent