BDBM340644 3-(5-acetyl-3-((4-(1-methyl-1H-pyrazol-4-yl)phenyl)amino)-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridin-1-yl)propanamide::US9763922, Example 171

SMILES CC(=O)N1CCc2c(C1)c(Nc1ccc(cc1)-c1cnn(C)c1)nn2CCC(N)=O

InChI Key InChIKey=ZTRUEZLVZHTHRR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 340644   

TargetCREB-binding protein(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 340644BDBM340644(US9763922, Example 171 | 3-(5-acetyl-3-((4-(1-meth...)
Affinity DataIC50: 60nMAssay Description:His/Flag epitope tagged CBP was cloned, expressed, and purified to homogeneity. CBP binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/30/2019
Entry Details
US Patent

TargetBromodomain-containing protein 4(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 340644BDBM340644(US9763922, Example 171 | 3-(5-acetyl-3-((4-(1-meth...)
Affinity DataIC50: 1.59E+4nMAssay Description:His/Flag epitope tagged BRD4 BD142-168 was cloned, expressed, and purified to. BRD4 binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/30/2019
Entry Details
US Patent