BDBM340729 US9763922, Example 255

SMILES CCCC(=O)N1CCc2c(C1)c(Nc1ccc(-c3cnn(C)c3)c(c1)C(F)F)nn2C1CCOC1

InChI Key InChIKey=BEHOQJKURPMQLR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 340729   

TargetCREB-binding protein(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 340729BDBM340729(US9763922, Example 255)
Affinity DataIC50: 854nMAssay Description:His/Flag epitope tagged CBP was cloned, expressed, and purified to homogeneity. CBP binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/30/2019
Entry Details
US Patent

TargetBromodomain-containing protein 4(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 340729BDBM340729(US9763922, Example 255)
Affinity DataIC50: 2.00E+4nMAssay Description:His/Flag epitope tagged BRD4 BD142-168 was cloned, expressed, and purified to. BRD4 binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/30/2019
Entry Details
US Patent