BDBM341887 US9771320, Example 121

SMILES Fc1ccc(cc1)S(=O)(=O)C1(CCCC1)c1ccc(cc1)C(OCc1cc(no1)-c1ccccc1C#N)(C(F)(F)F)C(F)(F)F

InChI Key InChIKey=OHFFBKGNEQOJND-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 341887   

TargetNuclear receptor ROR-gamma(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM341887(US9771320, Example 121)
Affinity DataIC50: 180nMAssay Description:The binding of potential ligands to RORγ is measured by competition with [3H] 25-hydroxycholesterol (Perkin Elmer NET674250UC) using a scintilla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/5/2019
Entry Details
Go to US Patent