BDBM342829 2-[4-(3-Dimethylamino-propionyl)-piperazin-1-ylmethyl]-thiazole-5-carboxylic acid 2,4-dichloro-benzylamide::US9776991, Example 199

SMILES CN(C)CCC(=O)N1CCN(Cc2ncc(s2)C(=O)NCc2ccc(Cl)cc2Cl)CC1

InChI Key InChIKey=AMHUBRQJHHMCON-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 342829   

TargetBifunctional epoxide hydrolase 2(Human)
Sanofi

US Patent
LigandPNGBDBM342829(2-[4-(3-Dimethylamino-propionyl)-piperazin-1-ylmet...)
Affinity DataIC50: 208nMAssay Description:Compounds were tested in a biochemical screening assay using recombinant sEH purified from Sf9 insect cells and an artificial substrate, (3-phenyl-ox...More data for this Ligand-Target Pair
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Date in BDB:
8/12/2019
Entry Details
US Patent