BDBM343104 N-3-isoxazolyl-1-(5-methoxy-2,2',4',5'-tetramethyl-4-biphenylyl)-6-isoquinolinesulfonamide::US9776995, Example 275

SMILES COc1cc(c(C)cc1-c1nccc2cc(ccc12)S(=O)(=O)Nc1ccon1)-c1cc(C)c(C)cc1C

InChI Key InChIKey=YCPKRHYIWYGGCX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 343104   

LigandPNGBDBM343104(N-3-isoxazolyl-1-(5-methoxy-2,2',4',5'-tetramethyl...)
Affinity DataIC50: 242nMAssay Description:HEK 293 cells stably transfected with human Nav1.7 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology sy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2019
Entry Details
US Patent