BDBM343737 (4-((5-(4-(3-(3,4-dihydroisoquinolin-2(1H)-yl)-2-hydroxypropoxy)phenyl)-1H-pyrazol-1-yl)methyl)phenyl)(pyrrolidin-1-yl)methanone::US9777008, Compound 31

SMILES OC(COc1ccc(cc1)-c1ccnn1Cc1ccc(cc1)C(=O)N1CCCC1)CN1CCc2ccccc2C1

InChI Key InChIKey=VLNLTELGECZHME-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 343737   

LigandChemical structure of BindingDB Monomer ID 343737BDBM343737((4-((5-(4-(3-(3,4-dihydroisoquinolin-2(1H)-yl)-2-h...)
Affinity DataIC50: 550nMAssay Description:The assays were all performed in a buffer consisting of 20 mM Bicine (pH=7.6), 1 mM TCEP, 0.005% BSG, and 0.002% Tween20, prepared on the day of use....More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2019
Entry Details
US Patent