BDBM34449 4-[(2-keto-1,3-dihydrobenzimidazol-5-yl)sulfonylamino]benzoic acid ethyl ester::4-[(2-oxo-1,3-dihydrobenzimidazol-5-yl)sulfonylamino]benzoic acid ethyl ester::MLS000049907::SMR000076986::US11787802, Example 43::cid_2210444::ethyl 4-[(2-oxidanylidene-1,3-dihydrobenzimidazol-5-yl)sulfonylamino]benzoate::ethyl 4-[(2-oxo-1,3-dihydrobenzimidazol-5-yl)sulfonylamino]benzoate::ethyl 4-{[(2-oxo-2,3-dihydro-1H-benzimidazol-5-yl)sulfonyl]amino}benzoate

SMILES CCOC(=O)c1ccc(NS(=O)(=O)c2ccc3[nH]c(=O)[nH]c3c2)cc1

InChI Key InChIKey=ZOJZDPRLQIFCHK-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 34449   

TargetDNA damage-binding protein 1/Protein cereblon(Human)
C4 Therapeutics

US Patent
LigandPNGBDBM34449(SMR000076986 | ethyl 4-[(2-oxo-1,3-dihydrobenzimid...)
Affinity DataKd:  100nMAssay Description:1) Optimization of measurement parameters to minimize protein consumption and to minimize the dilution effect and the DMSO content2) Titration measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2023
Entry Details
Go to US Patent

TargetGag-Pol polyprotein(HIV-1)
University of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM34449(SMR000076986 | ethyl 4-[(2-oxo-1,3-dihydrobenzimid...)
Affinity DataIC50: 1.79E+3nMpH: 8.0 T: 2°CAssay Description:A fluorescence resonance energy transfer assay is developed in 96-well and 384-well microplate formats with robotic manipulation to enable high-throu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2009
Entry Details
PCBioAssay