BDBM344800 1-[2-(1,4-dioxa-7-::1-[2-(1,4-dioxa-7-azaspiro[4.4]non-7-yl)-2-oxoethyl]-3-[1-(2-fluorophenyl)-1H-indazol-4-yl]imidazolidin-2-one::US9783527, Example 102

SMILES Fc1ccccc1-n1ncc2c(cccc12)N1CCN(CC(=O)N2CCC3(C2)OCCO3)C1=O

InChI Key InChIKey=SQWVKXAJZIGJIM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 344800   

TargetSodium channel protein type 9 subunit alpha(Human)
Abbvie

US Patent
LigandPNGBDBM344800(1-[2-(1,4-dioxa-7-azaspiro[4.4]non-7-yl)-2-oxoethy...)
Affinity DataIC50: 3.49E+3nMAssay Description:Two days prior to the experiment, frozen HEK293 cells stably expressing recombinant human Nav1.7 were quickly thawed and plated at 25,000 cells/well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details
US Patent