BDBM344927 1-{[1-::1-{[1-(benzyloxy)cyclopropyl]methyl}-3-[1-(2-fluorophenyl)-1H-indazol-4-yl]imidazolidin-2-one::US9783527, Example 229

SMILES Fc1ccccc1-n1ncc2c(cccc12)N1CCN(CC2(CC2)OCc2ccccc2)C1=O

InChI Key InChIKey=WOJMKAPIDNAFEU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 344927   

TargetSodium channel protein type 9 subunit alpha(Human)
Abbvie

US Patent
LigandPNGBDBM344927(1-{[1-(benzyloxy)cyclopropyl]methyl}-3-[1-(2-fluor...)
Affinity DataIC50: 9.08E+3nMAssay Description:Two days prior to the experiment, frozen HEK293 cells stably expressing recombinant human Nav1.7 were quickly thawed and plated at 25,000 cells/well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details
US Patent